Wednesday, December 10, 2008

The Secret of GARLIC

In the mysterious story, it is often told that GARLIC (Allium sativum) and its unpleasant smell can expel evil creatures so people hang it on door and windows, or use it as necklace.

Actually, in the outside of mystical power that hasn’t proven yet, garlic has a power to kill evil creature that we usually call it as bacteria.

Beside that, garlic also can expel various diseases like cardiovascular disease, inflammation, hypertension, cancer, and multiple complications that is appeared by type 2 diabetes.

Garlic doesn’t only become popular thing to research in Indonesia, but also in international. One of research is done by Dr. H. Isensee from Tubingen University, Germany, that success to prove that garlic has power as cardio protective.

Several research has revealed that garlic extract which just be bruised, could bring down and kill some kind of bacteria included drug resistant bacteria. And Allicin, which contained in garlic, also is proven that it can protect body cells from material than can cause cancer, and could make slow the spreading of cancer cells.

A lot of scientific journals has propagated the benefit of garlic. And the conclusion always just one: Garlic is useful (and very reasonable being used as food material, although its smell can make breathing smell stinky).

However, there are 2 things that need attention in order to feel optimum power of garlic: Always use fresh garlic. Beside that, let garlic that has bruised for 10 minutes, in order to increase the Allicin.

GARLIC’S FUN FACTS

Onion has close relation with garlic.

Garlic actually has high vitamin C content.

People name garlic as “Stinky Rose” because its smell.

Do you know? The way that used for disappearing garlic’s unpleasant smell is brush it to the stainless steel surface.

Because of famed, in some areas in United States, arrange Garlic Festival every year.

Monday, December 8, 2008

Prohibited Medication During Pregnancy

Most women take some kind of drug, substance or medication during pregnancy, often without realizing the potential for harm. Drugs or medication which taken by the mother may cross the placenta and reach the developing fetus. The possible effects may include prenatal death (stillbirth), developmental delay, intellectual disability and birth defects.

Therefore, US FDA (Food and Drug Administration) creates a system for rating drugs in terms of their safety during pregnancy. This system rates both over-the-counter (OTC) drugs you can buy in a drug or discount store, and drugs your health care provider prescribes. But most medicines have not been studied in pregnant women to see if they cause damage to the growing fetus.


The FDA system ranks drugs as:

· Category A – drugs that have been tested for safety during pregnancy and have been found to be safe.

· Category B - drugs that have been used a lot during pregnancy and do not appear to cause major birth defects or other problems.

· Category C - drugs that are more likely to cause problems for the mother or fetus. Also includes drugs for which safety studies have not been finished. The majority of these drugs do not have safety studies in progress. These drugs often come with a warning that they should be used only if the benefits of taking them outweigh the risks. This is something a woman would need to carefully discuss with her doctor.

· Category D - drugs that have clear health risks for the fetus

· Category X - drugs that have been shown to cause birth defects and should never be taken during pregnancy.

The list of drugs which is prohibited during pregnancy and the efect to the baby are:

Medication

Possible Effects

Androgens (male hormones)

Ambiguous genital development (depends on dose given and time when given)

Anticoagulants (warfarin)

Bone and hand abnormalities, intrauterine-growth retardation, central-nervous-system abnormalities, eye abnormalities

Antithyroid drugs (propylthiouracil, iodide, methimazole)

Hypothyroidism, fetal goiter

Chemotherapeutic drugs (methotrexate, aminopterin)

Increased risk of miscarriage

Isotretinoin (Accutane)

Increased miscarriage rate, nervous-system defects, facial defects, cleft palate

Lithium

Congenital heart disease

Phenytoin (Dilantin)

Growth retardation, mental retardation, microcephaly

Streptomycin

Hearing loss, cranial-nerve damage

Tetracycline

Hypoplasia of tooth enamel, discoloration of permanent teeth

Thalidomide

Severe limb defects

Trimethadione

Cleft lip, cleft palate, growth retardation, miscarriage

Valproic acid

Neural-tube defects

There are still a lot of drugs, which haven’t tested yet for pregnant women. So it is good for you or your wife for seeking advice from your doctor before you take some medication.

Sunday, November 30, 2008

Headache Usually Occur at a Person with Digestive Tract Problem

The latest research mentions that headache prevalence is higher at person with digestive tract disease symptoms like nausea, gastric acid reflux, and constipation than person that doesn’t have these symptoms. This research is published in Cephalgia Journal 2008.

Both of headache and gastritis symptoms are usually occurred to the population and depleting a lot of money. However, scientific literature, about headache and digestive tract complaint comorbidity, isn’t adequate enough. For investigating this problem, Dr.Anne Hege Aamodt and her colleague from Norwegian University of Science and Technology, reconsider a survey that is filled by 43.732 participants at Nord Trondelag Health Study included signs and symptoms of digestive tract disease and headache.

Had adjusted toward gender, age, depression, frightened, and the other factor that maybe influencing the result, The team found a higher prevalence of headache between participant that got reflux, diarrhea, constipation, and nausea than they who didn’t get these symptoms. The relation between headache and digestive tract complaint obviously rises with the increase of headache frequency, said Aamodt.

This result impacted the treatment for patients with headache. The important thing is to prevent the treatment of headache using drug with side effect at digestive tract that hasn’t got comfortable. The strong relevancy between headache frequency and digestive tract complaint frequency rise a number of question about the general mechanism that a patient with headache would get digestive tract complaint.


Source: Cephalgia Journal 2008

Thursday, November 27, 2008

Diabetes Mellitus (part1)

Almost everyone knows someone who has diabetes. An estimated 20.8 million people in the United States—7.0 percent of the population—have diabetes, a serious, lifelong condition. Of those, 14.6 million have been diagnosed, and 6.2 million have not yet been diagnosed. In 2005, about 1.5 million people aged 20 or older were diagnosed with diabetes.

Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin, or alternatively, when the body cannot effectively use the insulin it produces. Insulin is a hormone that regulates blood sugar. Hyperglycaemia, or raised blood sugar, is a common effect of uncontrolled diabetes and over time leads to serious damage to many of the body's systems, especially the nerves and blood vessels.

To understand diabetes, it is important to first understand the normal process by which food is broken down and used by the body for energy. Several things happen when food is digested:

  • A sugar called glucose enters the bloodstream. Glucose is a source of fuel for the body.
  • An organ called the pancreas makes insulin. The role of insulin is to move glucose from the bloodstream into muscle, fat, and liver cells, where it can be used as fuel.

People with diabetes have high blood sugar. This is because:

  • Their pancreas does not make enough insulin
  • Their muscle, fat, and liver cells do not respond to insulin normally
  • Both of the above

TYPES OF DIABETES

There are three major types of diabetes:

  • Type 1 diabetes is usually diagnosed in childhood. Many patients are diagnosed when they are older than age 20. In this disease, the body makes little or no insulin. Daily injections of insulin are needed. The exact cause is unknown. Genetics, viruses, and autoimmune problems may play a role.
  • Type 2 diabetes is far more common than type 1. It makes up most of diabetes cases. It usually occurs in adulthood, but young people are increasingly being diagnosed with this disease. The pancreas does not make enough insulin to keep blood glucose levels normal, often because the body does not respond well to insulin. Many people with type 2 diabetes do not know they have it, although it is a serious condition. Type 2 diabetes is becoming more common due to increasing obesity and failure to exercise.
  • Gestational diabetes is high blood glucose that develops at any time during pregnancy in a woman who does not have diabetes.

RISK FACTOR

There are a lot risk factors for type 2 diabetes, including:

  • Age > 45 years
  • A parent, brother, or sister with diabetes
  • Gestational diabetes or delivering a baby weighing more than 9 pounds (4 kgs)
  • Having heart disease
  • High blood cholesterol level
  • Obesity (BMI>30)
  • Not getting enough exercise
  • Previous impaired glucose tolerance
  • Some ethnic groups (particularly African Americans, Native Americans, Asians, Pacific Islanders, and Hispanic Americans)

SYMPTOMS

High blood levels of glucose can cause several problems, including:

  • Blurry vision
  • Excessive thirst
  • Fatigue
  • Frequent urination
  • Hunger
  • Weight loss

However, because type 2 diabetes develops slowly, some people with high blood sugar experience no symptoms at all.

Symptoms of type 1 diabetes:

  • Fatigue
  • Increased thirst
  • Increased urination
  • Nausea
  • Vomiting
  • Weight loss in spite of increased appetite

Patients with type 1 diabetes usually develop symptoms over a short period of time. The condition is often diagnosed in an emergency setting.

Symptoms of type 2 diabetes:

  • Blurred vision
  • Fatigue
  • Increased appetite
  • Increased thirst

EXAMS AND TESTS

A urine analysis may be used to look for glucose and ketones from the breakdown of fat. However, a urine test alone does not diagnose diabetes.

The following blood glucose tests are used to diagnose diabetes:

  • Fasting blood glucose level -- diabetes is diagnosed if higher than 126 mg/dL on two occasions. Levels between 100 and 126 mg/dL are referred to as impaired fasting glucose or pre-diabetes. These levels are considered to be risk factors for type 2 diabetes and its complications.
  • Oral glucose tolerance test -- diabetes is diagnosed if glucose level is higher than 200 mg/dL after 2 hours. (This test is used more for type 2 diabetes.)
  • Non Fasting blood glucose level -- diabetes is suspected if higher than 200 mg/dL and accompanied by the classic diabetes symptoms of increased thirst, urination, and fatigue. (This test must be confirmed with a fasting blood glucose test.)

You need your Hemoglobin A1c (HbA1c) level checked every 3 - 6 months. The HbA1c is a measure of average blood glucose during the previous 2 - 3 months. It is a very helpful way to determine how well treatment is working.


Source : WHO and CDC

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